This study examined the effects of 2.6 g/d of phytosterol ingestion on LDL cholesterol metabolism. It is expected that this dose will significantly reduce LDL cholesterol after 12 weeks of supplementation.
Full Title of Study: “Effectiveness of Phytosterol Supplementation on Select Indices of Cardiovascular Risk”
- Study Type: Interventional
- Study Design
- Allocation: Randomized
- Intervention Model: Single Group Assignment
- Primary Purpose: Prevention
- Masking: Single
This study examined the effects of 2.6 g/d of phytosterol ingestion on LDL cholesterol metabolism. It is expected that this dose will significantly reduce LDL cholesterol after 12 weeks of supplementation. The study recruited 72 men and women 20-70 years of age with mild hypercholesteremia (>130 mg/dl LDL-C). They were assigned to 1 of 2 groups. Participants ingested the supplement or a placebo for 12 weeks, with an interim assessment at 6 weeks. Participants agreed to maintain current diet, medication, and exercise habits and to not donate blood during the trial.
- Drug: phytosterol
Clinical Trial Outcome Measures
- Ingestion of the supplement will result in reduced LDL cholesterol.
Participating in This Clinical Trial
- mild hypercholesteremia, sign informed consent, not donate blood, maintain diet and exercise habits Exclusion Criteria:
- BMI <18.5 or >34.9, recent blood donation, serious or life-threatening disease
Gender Eligibility: All
Minimum Age: 20 Years
Maximum Age: 70 Years
Are Healthy Volunteers Accepted: Accepts Healthy Volunteers
- Lead Sponsor
- The Cooper Institute
- Overall Official(s)
- Conrad Earnest, PhD, Principal Investigator, The Cooper Institute
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