Brain Imaging and Pain in Irritable Bowel Syndrome


This study examines the mechanisms, including brain imaging of placebo analgesia

Full Title of Study: “Brain Imaging and Pain: Analysis of Placebo Analgesia”

Study Type

  • Study Type: Interventional
  • Study Design
    • Allocation: Randomized
    • Intervention Model: Factorial Assignment
    • Masking: Double
  • Study Primary Completion Date: December 2007


  • Drug: placebo

Participating in This Clinical Trial

Inclusion Criteria

  • Irritable Bowel Syndrome
  • English speaking

Exclusion Criteria

  • Chronic pain condition other than Irritable Bowel Syndrome
  • Medical condition that would contraindicate use of lidocaine
  • Clinical criteria for fibromyalgia
  • Presence of systemic disease such as diabetes, thyroid, gastrointestinal or liver disease, collagen vascular disease, malignancy, focal or neurological
  • Seropositive HIV
  • Pregnancy

Gender Eligibility: All

Minimum Age: 18 Years

Maximum Age: 70 Years

Are Healthy Volunteers Accepted: No

Investigator Details

  • Lead Sponsor
    • University of Florida
  • Collaborator
    • National Center for Complementary and Integrative Health (NCCIH)
  • Provider of Information About this Clinical Study
    • Sponsor
  • Overall Official(s)
    • Michael E Robinson, PhD, Principal Investigator, University of Florida

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